I have read @vortex post on How to Cut Placements, Landers and Banners and I see it focused on low payout offers where you get enought traffic and conversions to cut placement but how do you do it with high payout offers? With landers and banners it is easier - if I run 4 landers and decide to cut on low CR or no conversions at 3x payout. But having 100s and even 1000s of placelent (zone IDs) needs huge budget to cut low performing zones based on statistical significance. How do you optimize a campaign with say $10 payout per conversion?
Try to run a similar offer that has lower payout first, to cut placements, then run the higher-payout offer. For example if you're running a CC submit offer, try a SOI in the same vertical.
Another thing to try that can potentially curb the spend: Identify bigger traffic segment(s) that have high/low ROI and white/blacklist them to optimize to profitability faster.
Let's see what else push experts recommend - my knowledge is limited when it comes to this traffic type.
Amy