I recently started a native campaign, and I am hearing mixed reviews on Straight sales profitability/ Effectiveness on Native. I am also wondering what are the best ways to optimize/Scale. Any input would be greatly appreciated!
You're talking about nutra SS or something else? And this is your first native campaign?
High cost to consumer, high payout straightsales are among the hardest things you can test on native with sources that have lots of placements. It's easier to switch over from trials after you've built up whitelists and found the winning creatives.